蘭立生物已經(jīng)建立并驗(yàn)證的模型:
1. 皮下接種模型
腫瘤類型
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模型
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Bladder
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5637,HT1376,RT4,RT112/84,UM-UC-1
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Blood/Leukemia
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ARH-77,EOL-1,HL-60,Jurkat clone E6-1,JVM-3,K-562,Kasumi-1,L-363,ML-2, MOLM-13,MOLM-16,MOLT-4,MV-4-11,NALM-6,RS4;11,THP-1,KG-1 ,PEER
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Blood/Lymphoma
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CA46,Daudi,DOHH-2,GRANTA-519,JeKo-1,KARPAS-299,KARPAS-422,NAMALWA,OCI-LY19,OCI-LY7,Pfei?er,Raji,Ramos,RL,SU-DHL-1,SU-DHL-2,SU-DHL-6,SU-DHL-8, SU-DHL-10,U-937,WSU-DLCL2,Z-138,HUT102,L-540
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Blood/Myeloma
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AMO-1,MM.1R,MM.1S,MOLP8,NCI-H929,OPM2,RPMI 8226,U266B1,JJN-3
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Bone
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143B,SJSA-1,SK-ES-1
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Brain&Nerves
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LN-229,SF268,U-118 MG,U-87 MG,IMR-32
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Breast
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BT-474,DU4475,HCC1954,JIMT-1,MCF7,MX-1,ZR-75-1,HCC1806,HCC1187,HCC1569,T47D, MDA-MB-231,MDA-MB-134,MDA-MB-468,MAD-MB-436,MDA-MB-435
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Head&Neck
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KYSE-150,KYSE-270,KYSE-410,OE19,C666-1,F(xiàn)aDu,CAL-27,SCC-4,Detroit562,EC109, T.T,TT
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Kidney
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786-O,A498,Caki-1
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Colorectum
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COLO 205,COLO 320DM,DLD-1,HCT 116,HCT-15,HT-29,LoVo,LS 174T,LS411N,RKO,SNU-81,SW48,SW480,SW620,SW948,T84,SW837,HT55,KM12L4,NCI-H716
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Liver
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HCCLM3,HEP G2,HEP G2/C3A,HEP3B,HUH-1,HUH-7,JHH-5,JHH-7,MHCC97-H,PLC/PRF/5, SK-HEP-1,SNU-761,SNU-878,HUCCT1
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Lung
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A549,CALU-3,CALU-6,COR-L23,DMS 114,EBC-1,H69AR,HCC1359,HCC4006,HCC827,HCC827-ER1, NCI-H1048,NCI-H1155,NCI-H1299,NCI-H1417,NCI-H146,NCI-H1581,NCI-H1650,NCI-H1703,NCI-H1781, NCI-H1975,NCI-H1993,NCI-H2023,NCI-H209,NCI-H2110,NCI-H2122,NCI-H2228,NCI-H292,NCI-H358, NCI-H441,NCI-H446,NCI-H460,NCI-H520,NCI-H526,NCI-H568,NCI-H69,NCI-H727,NCI-H82,NCI-H820, NCI-H838,NCI-H889,PC-9,RERF-LC-A1,RERF-LC-AD1,SK-MES-1,SNU-2535,MSTO 211H,NCI-H226
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Ovary
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A2780,ES-1,IGR-OV1,OVCAR-3,OVCAR-8,PA-1,RMG-1,SK-OV-3,TOV112D,TOV-21G
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Pancreas
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AsPC-1,BxPC-3,Capan-1,Capan-2,HPAC,HPAF-II,Hs766T,HUP-T3,KP4,MIA PaCa-2,PANC-1, PANC 02.13,PANC 03.27,PANC 05.04
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Skin
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A2058,A-375,A-431,SK-MEL-28,SK-MEL-5,MeWo
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Gastric
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HGC-27,HS 746.T,MKN45,NCI-N87,NUGC-4,SNU-5,SNU-16,YCC-2,YCC-10,SNU601,SNU620
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Uterus
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AN3 CA,Ishikawa
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Prostate
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22RV1,C4-2,DU 145,LNCaP clone FGC,NCI-H660,PC-3,PC-3M,VCAP
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Other
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HT1080,NCI-H295R,A-673,JEG-3,HeLa,SiHa
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2、熒光素酶標(biāo)記CDX模型
SK-OV-3-Luc,Nalm6-Luc,Nalm6-Luc-CD19 KO,Nalm6-Luc-CD22 KO,Nalm6-Luc-CD19/CD22 KO,Raji-Luc,Raji -PDL1-Luc, Raji-Luc-CD19 KO,Raji-Luc-CD22 KO,Raji-Luc-CD19/CD22 KO,MV-4-11 Luc,MM.1S-Luc,MCF7-Luc,JeKo-1-Luc,HUH-7 Luc,A549Luc,DU 145 Luc2,DU 145 Luc hGDF-15FL,DU 145 Luc hGDF-15MP, RPMI-8226-Luc,U87-MG-Luc
3、原位接種模型轉(zhuǎn)移模型等
蘭立生物還提供原位模型,白血病全身腫瘤模型,腫瘤轉(zhuǎn)移模型,基因改造腫瘤模型,詳情請(qǐng)咨詢info@lanlybio.com。